Why INTRON® A for Malignant Melanoma?

The only drug proven to improve survival in people with high-risk malignant melanoma

High-risk melanomas are tumors of the skin that have a high chance of coming back, or have spread to nearby lymph nodes. A tumor is considered a "high-risk" melanoma if:

• it is more than 4 millimeters thick (approximately 1/6 of an inch)

OR

• it has spread to the body tissue below the skin to a lymph node

INTRON® A is used to treat these high-risk melanomas within 8 weeks of surgery.

INTRON® A is the one and only medication for people with high-risk malignant melanoma that has been shown to improve both:

• relapse-free survival (living without the disease coming back)

and

• overall survival

The majority of people taking INTRON® A are able to tolerate a full 52-week course of medication, with appropriate management by their doctor. This may include changes in dosing.

INTRON® A (Interferon alfa-2b, recombinant) for Injection is a treatment meant for melanoma patients 18 years of age or older, whose tumors have been surgically removed but are at high risk for coming back. INTRON® A must be used within 56 days (8 weeks) after surgery.